Cargando…

Tumor Mutation Burden Prediction Model in Egyptian Breast Cancer patients based on Next Generation Sequencing

OBJECTIVES: This study aimed to identify the tumor mutation burden (TMB) value in Egyptian breast cancer (BC) patients. Moreover, to find the best TMB prediction model based on the expression of estrogen (ER), progesterone (PR), human epidermal growth factor receptor 2 (HER-2), and proliferation ind...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nassar, Auhood, Lymona, Ahmed M, Lotfy, Mai M, Youssef, Amira Salah El-Din, Mohanad, Marwa, Manie, Tamer M, Youssef, Mina M G, Farahat, Iman G, Zekri, Abdel-Rahman N
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	West Asia Organization for Cancer Prevention 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607104/ https://www.ncbi.nlm.nih.gov/pubmed/34319027 http://dx.doi.org/10.31557/APJCP.2021.22.7.2053

Ejemplares similares

Somatic Mutations Alter Interleukin Signaling Pathways in Grade II Invasive Breast Cancer Patients: An Egyptian Experience
por: Nassar, Auhood, et al.
Publicado: (2022)

Frequency of Pathogenic Germline Mutations in Early and Late Onset Familial Breast Cancer Patients Using Multi-Gene Panel Sequencing: An Egyptian Study
por: Nassar, Auhood, et al.
Publicado: (2022)

Targeted next generation sequencing identifies somatic mutations in a cohort of Egyptian breast cancer patients
por: Nassar, Auhood, et al.
Publicado: (2020)

Multigene Panel Sequencing Reveals Cancer-Specific and Common Somatic Mutations in Colorectal Cancer Patients: An Egyptian Experience
por: Youssef, Amira Salah El-Din, et al.
Publicado: (2022)

Circulating Serum miRNAs as Diagnostic Markers for Colorectal Cancer
por: Zekri, Abdel-Rahman N., et al.
Publicado: (2016)

Long non-coding RNAs as novel prognostic biomarkers for breast cancer in Egyptian women
por: El-Helkan, Basma, et al.
Publicado: (2022)

MicroRNA Signatures for circulating CD133-positive cells in hepatocellular carcinoma with HCV infection
por: Zekri, Abdel-Rahman N., et al.
Publicado: (2018)

The possible role of Dickkopf-1, Golgi protein- 73 and Midkine as predictors of hepatocarcinogenesis: a review and an Egyptian study
por: N Zekri, Abdel-Rahman, et al.
Publicado: (2020)

Genome sequencing of SARS-CoV-2 in a cohort of Egyptian patients revealed mutation hotspots that are related to clinical outcomes
por: Zekri, Abdel-Rahman N., et al.
Publicado: (2021)

Lateral chest wall perforator flaps in partial breast reconstruction
por: Orabi, Ahmed, et al.
Publicado: (2022)

Predictors of Serum 25-Hydroxyvitamin D Concentrations among a Sample of Egyptian Schoolchildren
por: Abu Shady, Mones M., et al.
Publicado: (2016)

Association of Serum 25-Hydroxyvitamin D with Life Style and Dietary Factors in Egyptian Prepubescent Children
por: Shady, Mones M. Abu, et al.
Publicado: (2015)

Peripheral vein infusion of autologous mesenchymal stem cells in Egyptian HCV-positive patients with end-stage liver disease
por: Salama, Hosny, et al.
Publicado: (2014)

Occult HBV infection among Egyptian hepatocellular carcinoma patients
por: Hassan, Zeinab K, et al.
Publicado: (2011)

Preoperative estimation of cosmetic outcomes after immediate breast reconstruction with extended latissimus dorsi flap: A simple prediction model
por: Manie, T., et al.
Publicado: (2017)

A comparison of the performance of normal middle social class Egyptian infants and toddlers with the reference norms of the Bayley Scales -third edition (Bayley III): A pilot study
por: Salah El-Din, Ebtissam M., et al.
Publicado: (2021)

Investigation of chromosomal aberrations in Egyptian hepatocellular carcinoma patients by fluorescence in situ hybridization
por: Aly, Magdy S., et al.
Publicado: (2010)

Evaluation of Amino Acids Profile as Non-Invasive Biomarkers of Hepatocellular Carcinoma in Egyptians
por: Ghanem, Samar Ebrahim, et al.
Publicado: (2022)

The Prevalence and Risk Factors of Early Arrhythmias Following Pediatric Open Heart Surgery in Egyptian Children
por: Gawad, Tarek Ahmed Abdel, et al.
Publicado: (2017)

Potential Diagnostic and Prognostic Value of Lymphocytic Mitochondrial DNA Deletion in Relation to Folic Acid Status in HCV-Related Hepatocellular Carcinoma
por: Zekri, Abdel Rahman N, et al.
Publicado: (2017)

Immunostimulant Effect of Egyptian Propolis in Rabbits
por: Nassar, Somya A., et al.
Publicado: (2012)

Genotypic Characterization of Carbapenem-Resistant Klebsiella pneumoniae Isolated from an Egyptian University Hospital
por: Taha, Marwa S., et al.
Publicado: (2023)

Reasons behind high rate of non-compliance to scheduled office visits in hypertensive patients: results from the Egyptian registry of specialized hypertension clinics
por: Youssef, Ghada, et al.
Publicado: (2022)

Prognostic Impact of BRCA1 and BRCA2 Mutations on Long-Term Survival Outcomes in Egyptian Female Breast Cancer Patients
por: AbdelHamid, Sherihan, et al.
Publicado: (2021)

Association between genotype and disease complications in Egyptian patients with beta thalassemia: A Cross-sectional study
por: Hassan, Tamer, et al.
Publicado: (2018)

Genetic distance and heterogenecity between quasispecies is a critical predictor to IFN response in Egyptian patients with HCV genotype-4
por: Zekri, Abdel Rahman N, et al.
Publicado: (2007)

Protective Effect of Egyptian Propolis against Rabbit Pasteurellosis
por: Nassar, Somia A., et al.
Publicado: (2013)

Prevalence of Subclinical Keratoconus Among Pediatric Egyptian Population with Astigmatism
por: Sidky, Mohamed Karim, et al.
Publicado: (2020)

MEFV gene mutations in Egyptian children with Henoch-Schonlein purpura
por: Salah, Samia, et al.
Publicado: (2014)

Association of Fascin and matrix metalloproteinase-9 expression with poor prognostic parameters in breast carcinoma of Egyptian women
por: Youssef, Nermeen Salah, et al.
Publicado: (2014)

Transforming growth factor-β, insulin-like growth factor I/insulin-like growth factor I receptor and vascular endothelial growth factor-A: Prognostic and predictive markers in triple-negative and non-triple-negative breast cancer
por: BAHHNASSY, ABEER, et al.
Publicado: (2015)

Status of serum magnesium in Egyptian children with type 1 diabetes and its correlation to glycemic control and lipid profile
por: Shahbah, Doaa, et al.
Publicado: (2016)

The Egyptian Arabic version of the Juvenile Arthritis Multidimensional Assessment Report (JAMAR)
por: El Miedany, Yasser, et al.
Publicado: (2018)

001 Egyptian consensus-based recommendations for the diagnosis and targeted management of Kawasaki disease. An initiative by the Egyptian College of Pediatric Rheumatology
por: El Miedany, Y, et al.
Publicado: (2022)

Difference in plaque characteristics of coronary culprit lesions in a cohort of Egyptian patients presented with acute coronary syndrome and stable coronary artery disease: An optical coherence tomography study
por: ElFaramawy, Amr, et al.
Publicado: (2018)

Surveillance, isolation and complete genome sequence of bovine parainfluenza virus type 3 in Egyptian cattle
por: Sobhy, Nader M., et al.
Publicado: (2017)

Review of the utilization of HEEPF – competitive projects for educational enhancement in the Egyptian medical sector
por: Abdellah, Galal Abdel-Hamid, et al.
Publicado: (2008)

Study of selective immunoglobulin A deficiency among Egyptian patients with food allergy
por: SHAHIN, RASHA YOUSSEF, et al.
Publicado: (2020)

Nomogram of age-specific anti-Müllerian hormone levels in healthy Egyptian females
por: El-Attar, Eman Ahmed, et al.
Publicado: (2021)

Blindness and Visual Impairment among Egyptian Glaucoma Patients
por: Eldaly, M. A., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_9h14ng416vkeag3auf1bs196n0