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A novel role of KEAP1/PGAM5 complex: ROS sensor for inducing mitophagy

When ROS production exceeds the cellular antioxidant capacity, the cell needs to eliminate the defective mitochondria responsible for excessive ROS production. It has been proposed that the removal of these defective mitochondria involves mitophagy, but the mechanism of this regulation remains uncle...

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Detalles Bibliográficos
Autores principales:	Zeb, Akbar, Choubey, Vinay, Gupta, Ruby, Kuum, Malle, Safiulina, Dzhamilja, Vaarmann, Annika, Gogichaishvili, Nana, Liiv, Mailis, Ilves, Ivar, Tämm, Kaido, Veksler, Vladimir, Kaasik, Allen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607199/ https://www.ncbi.nlm.nih.gov/pubmed/34801863 http://dx.doi.org/10.1016/j.redox.2021.102186

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