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The combination therapy of oncolytic HSV-1 armed with anti-PD-1 antibody and IL-12 enhances anti-tumor efficacy

Cancer immunotherapy is a new therapeutic strategy for cancer treatment that targets tumors by improving or restoring immune system function. Therapies targeting immune checkpoint molecules have exerted potent anti-tumor effects and prolonged the overall survival rate of patients. However, only a sm...

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Detalles Bibliográficos
Autores principales: Xie, Xin, Lv, Jingwen, Zhu, Wei, Tian, Chao, Li, Jingfeng, Liu, Jiajia, Zhou, Hua, Sun, Chunyang, Hu, Zongfeng, Li, Xiaopeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607272/
https://www.ncbi.nlm.nih.gov/pubmed/34808461
http://dx.doi.org/10.1016/j.tranon.2021.101287