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Targeted Nanotherapeutics Using LACTB Gene Therapy Against Melanoma

INTRODUCTION: β-lactamase (LACTB) is a tumor suppressor gene in various tumors including melanoma. However, it remains challenging to efficiently deliver the LACTB gene into melanoma. Recently, we designed a nonviral nanocarrier iRGD/DOTAP/MPEG-PDLLA (iDPP) that could deliver gene targetedly to mela...

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Detalles Bibliográficos
Autores principales:	Liu, Jinlu, Yang, Ling, Yuan, Xin, Xiong, Meimei, Zhu, Jiao, Wu, Wenbi, Ren, Min, Long, Jianlin, Xu, Xuewen, Gou, Maling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607278/ https://www.ncbi.nlm.nih.gov/pubmed/34819728 http://dx.doi.org/10.2147/IJN.S331519

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