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Real-time kinetic studies of Mycobacterium tuberculosis LexA–DNA interaction

Transcriptional repressor, LexA, regulates the ‘SOS’ response, an indispensable bacterial DNA damage repair machinery. Compared with its Escherichia coli ortholog, LexA from Mycobacterium tuberculosis (Mtb) possesses a unique N-terminal extension of additional 24 amino acids in its DNA-binding domai...

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Detalles Bibliográficos
Autores principales: Chatterjee, Chitral, Majumdar, Soneya, Deshpande, Sachin, Pant, Deepak, Matheshwaran, Saravanan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607333/
https://www.ncbi.nlm.nih.gov/pubmed/34792534
http://dx.doi.org/10.1042/BSR20211419