Detection of alternative lengthening of telomeres mechanism on tumor sections

The vast majority of adult cancer cells achieve cellular immortality by activating a telomere maintenance mechanism (TMM). While this is mostly achieved by the de-silencing of hTERT telomerase gene expression, an alternative homologous recombination-based and telomerase-independent mechanism, known...

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Detalles Bibliográficos
Autores principales: Claude, Eloïse, de Lhoneux, Guillaume, Pierreux, Christophe E., Marbaix, Etienne, de Ville de Goyet, Maëlle, Boulanger, Cécile, Van Damme, An, Brichard, Bénédicte, Decottignies, Anabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607387/
https://www.ncbi.nlm.nih.gov/pubmed/35006465
http://dx.doi.org/10.1186/s43556-021-00055-y

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