Cargando…

G-protein coupled receptor, PI3K and Rho signaling pathways regulate the cascades of Tau and amyloid-β in Alzheimer’s disease

Alzheimer’s disease is a progressive neurodegenerative disease characterized by the presence of amyloid-β plaques in the extracellular environment and aggregates of Tau protein that forms neurofibrillary tangles (NFTs) in neuronal cells. Along with these pathological proteins, the disease shows neur...

Descripción completa

Detalles Bibliográficos
Autores principales:	Desale, Smita Eknath, Chidambaram, Hariharakrishnan, Chinnathambi, Subashchandrabose
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Singapore 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607389/ https://www.ncbi.nlm.nih.gov/pubmed/35006431 http://dx.doi.org/10.1186/s43556-021-00036-1

Ejemplares similares

α– Linolenic acid modulates phagocytosis and endosomal pathways of extracellular Tau in microglia
por: Desale, Smita Eknath, et al.
Publicado: (2021)

α-Linolenic acid induces clearance of Tau seeds via Actin-remodeling in Microglia
por: Desale, Smita Eknath, et al.
Publicado: (2021)

Role of dietary fatty acids in microglial polarization in Alzheimer’s disease
por: Desale, Smita Eknath, et al.
Publicado: (2020)

Phosphoinositides signaling modulates microglial actin remodeling and phagocytosis in Alzheimer’s disease
por: Desale, Smita Eknath, et al.
Publicado: (2021)

Interaction of Tau with the chemokine receptor, CX3CR1 and its effect on microglial activation, migration and proliferation
por: Chidambaram, Hariharakrishnan, et al.
Publicado: (2020)

Basic Limonoid modulates Chaperone-mediated Proteostasis and dissolve Tau fibrils
por: Gorantla, Nalini Vijay, et al.
Publicado: (2020)

EGCG impedes human Tau aggregation and interacts with Tau
por: Sonawane, Shweta Kishor, et al.
Publicado: (2020)

Methylation as a key regulator of Tau aggregation and neuronal health in Alzheimer’s disease
por: Balmik, Abhishek Ankur, et al.
Publicado: (2021)

TGF-β1 signalling in Alzheimer’s pathology and cytoskeletal reorganization: a specialized Tau perspective
por: Kapoor, Mahima, et al.
Publicado: (2023)

Protein-Capped Metal Nanoparticles Inhibit Tau Aggregation in Alzheimer’s Disease
por: Sonawane, Shweta Kishor, et al.
Publicado: (2019)

Photoexcited Toluidine Blue Inhibits Tau Aggregation in Alzheimer’s Disease
por: Dubey, Tushar, et al.
Publicado: (2019)

Amyloid-β-Derived Peptidomimetics Inhibits Tau Aggregation
por: Gorantla, Nalini V., et al.
Publicado: (2021)

Molecular Cobalt(II) Complexes for Tau Polymerization in Alzheimer’s Disease
por: Gorantla, Nalini Vijay, et al.
Publicado: (2019)

Baicalein inhibits heparin-induced Tau aggregation by initializing non-toxic Tau oligomer formation
por: Sonawane, Shweta Kishor, et al.
Publicado: (2021)

Epigallocatechin-3-gallate modulates Tau Post-translational modifications and cytoskeletal network
por: Sonawane, Shweta Kishor, et al.
Publicado: (2021)

Microglia degrade Tau oligomers deposit via purinergic P2Y12-associated podosome and filopodia formation and induce chemotaxis
por: Chinnathambi, Subashchandrabose, et al.
Publicado: (2023)

Phagocytosis of full-length Tau oligomers by Actin-remodeling of activated microglia
por: Das, Rashmi, et al.
Publicado: (2020)

Melatonin Reduces GSK3β-Mediated Tau Phosphorylation, Enhances Nrf2 Nuclear Translocation and Anti-Inflammation
por: Das, Rashmi, et al.
Publicado: (2020)

Neem Derivatives Inhibits Tau Aggregation
por: Gorantla, Nalini V., et al.
Publicado: (2021)

The extracellular HDAC6 ZnF UBP domain modulates the actin network and post-translational modifications of Tau
por: Balmik, Abhishek Ankur, et al.
Publicado: (2021)

Neem Derivatives Inhibits Tau Aggregation(1)
por: Gorantla, Nalini V., et al.
Publicado: (2019)

Measurement of the tau neutrino helicity in the decays tau --> pi-nu and tau --> rho-nu
por: Raab, J, et al.
Publicado: (1993)

Photodynamic exposure of Rose-Bengal inhibits Tau aggregation and modulates cytoskeletal network in neuronal cells
por: Dubey, Tushar, et al.
Publicado: (2020)

Author Correction: Photodynamic exposure of Rose-Bengal inhibits Tau aggregation and modulates cytoskeletal network in neuronal cells
por: Dubey, Tushar, et al.
Publicado: (2022)

Measurement of rho meson production rates in the tau --> pi pi^o channel
por: Bourdon, P
Publicado: (1994)

Anti-Amyloid Therapies for Alzheimer’s Disease and the Amyloid Cascade Hypothesis
por: Fedele, Ernesto
Publicado: (2023)

Measurement of the hepicity of the neutrino produced in tau --> pi-nu and tau --> rho-nu decays
por: Snow, S, et al.
Publicado: (1993)

Study of $\tau$ decays to $K K \pi$ and $K \pi \pi$ at LEP, with DELPHI
por: Cavallo, F R
Publicado: (1997)

Limits on the couplings of $\rho^{'}$ (1300 MrV) and $\rho^{''}$ (1700 MrV) to the photon and to the ($\pi\pi$) system
por: Bollini, D, et al.
Publicado: (1976)

Apolipoprotein E: Essential Catalyst of the Alzheimer Amyloid Cascade
por: Potter, Huntington, et al.
Publicado: (2012)

Photoproduction at the SPS: $-\phi$, $\rho'$, K$^+$ K$^-$ $\pi^+$ $\pi^-$ and a search for charmed mesons
por: Kemp, A
Publicado: (1978)

Tau-Id performance to separate tau leptons with helicity +1 and -1 using $\tau\to a_{1}\nu\to 3\pi^{\pm}\nu$ and $\tau\to\rho\nu\to\pi^{\pm}\pi^0\nu$ decays
por: CMS Collaboration
Publicado: (2016)

Reconsideration of Amyloid Hypothesis and Tau Hypothesis in Alzheimer's Disease
por: Kametani, Fuyuki, et al.
Publicado: (2018)

The Dichotomy of Alzheimer’s Disease Pathology: Amyloid-β and Tau
por: Ashford, J. Wesson
Publicado: (2019)

Alzheimer's Disease and the Amyloid Cascade Hypothesis: A Critical Review
por: Reitz, Christiane
Publicado: (2012)

The Pathogenesis of Alzheimer's Disease: A Reevaluation of the “Amyloid Cascade Hypothesis”
por: Armstrong, R. A.
Publicado: (2011)

Amyloid Cascade Hypothesis for the Treatment of Alzheimer’s Disease: Progress and Challenges
por: Wu, Tong, et al.
Publicado: (2022)

Analysis of the decay tau(+-) to rho(+-)nu tau
por: CERN. Geneva
Publicado: (1992)

Photon diffractive dissociation to rho$\varrho$pi and rho$\pi$pi.pi states
por: Atkinson, M, et al.
Publicado: (1988)

Detection of Alzheimer's disease amyloid beta 1‐42, p‐tau, and t‐tau assays
por: van Harten, Argonde C., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ka315hbenfs9cf0ko6543o8gt9