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CHD1 controls H3.3 incorporation in adult brain chromatin to maintain metabolic homeostasis and normal lifespan

The ATP-dependent chromatin remodeling factor CHD1 is essential for the assembly of variant histone H3.3 into paternal chromatin during sperm chromatin remodeling in fertilized eggs. It remains unclear, however, if CHD1 has a similar role in normal diploid cells. Using a specifically tailored quanti...

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Detalles Bibliográficos
Autores principales:	Schoberleitner, Ines, Bauer, Ingo, Huang, Anming, Andreyeva, Evgeniya N., Sebald, Johanna, Pascher, Katharina, Rieder, Dietmar, Brunner, Melanie, Podhraski, Valerie, Oemer, Gregor, Cázarez-García, Daniel, Rieder, Leila, Keller, Markus A., Winkler, Robert, Fyodorov, Dmitry V., Lusser, Alexandra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607513/ https://www.ncbi.nlm.nih.gov/pubmed/34610319 http://dx.doi.org/10.1016/j.celrep.2021.109769

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