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The health risks of dysphagia for patients with head and neck cancer: a multicentre prospective observational study

It is well known that malnutrition is a frequent co-morbidity in cancer patients, especially in those with head and neck neoplasms. This may be due both to the presence of dysphagia symptoms and to the appearance of adverse effects on chemotherapy and / or radiotherapy. The aim of this retrospective...

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Autores principales: Cristofaro, Maria Giulia, Barca, Ida, Ferragina, Francesco, Novembre, Daniela, Ferro, Yvelise, Pujia, Roberta, Montalcini, Tiziana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607588/
https://www.ncbi.nlm.nih.gov/pubmed/34809654
http://dx.doi.org/10.1186/s12967-021-03144-2
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author Cristofaro, Maria Giulia
Barca, Ida
Ferragina, Francesco
Novembre, Daniela
Ferro, Yvelise
Pujia, Roberta
Montalcini, Tiziana
author_facet Cristofaro, Maria Giulia
Barca, Ida
Ferragina, Francesco
Novembre, Daniela
Ferro, Yvelise
Pujia, Roberta
Montalcini, Tiziana
author_sort Cristofaro, Maria Giulia
collection PubMed
description It is well known that malnutrition is a frequent co-morbidity in cancer patients, especially in those with head and neck neoplasms. This may be due both to the presence of dysphagia symptoms and to the appearance of adverse effects on chemotherapy and / or radiotherapy. The aim of this retrospective observational multicentric study is to evaluate the nutritional status between dysphagia cancer patients and non-dysphagia cancer patients. Data from 60 patients were analysed, 31 of which without dysphagia and 29 with dysphagia. Results highlight that patients with dysphagia had higher involuntary body weight loss than non-dysphagia ones (p < 0.001). By analysing the entire population, it stands out a weight loss rate of 12 ± 9% compared to the usual weight was observed and a prevalence of moderate / severe malnutrition diagnosis of 53%. Furthermore, 76% of the population who manifested the symptom of dysphagia presented severe malnutrition already at the first visit, compared to 32% of non-dysphagia subjects.
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spelling pubmed-86075882021-11-22 The health risks of dysphagia for patients with head and neck cancer: a multicentre prospective observational study Cristofaro, Maria Giulia Barca, Ida Ferragina, Francesco Novembre, Daniela Ferro, Yvelise Pujia, Roberta Montalcini, Tiziana J Transl Med Research It is well known that malnutrition is a frequent co-morbidity in cancer patients, especially in those with head and neck neoplasms. This may be due both to the presence of dysphagia symptoms and to the appearance of adverse effects on chemotherapy and / or radiotherapy. The aim of this retrospective observational multicentric study is to evaluate the nutritional status between dysphagia cancer patients and non-dysphagia cancer patients. Data from 60 patients were analysed, 31 of which without dysphagia and 29 with dysphagia. Results highlight that patients with dysphagia had higher involuntary body weight loss than non-dysphagia ones (p < 0.001). By analysing the entire population, it stands out a weight loss rate of 12 ± 9% compared to the usual weight was observed and a prevalence of moderate / severe malnutrition diagnosis of 53%. Furthermore, 76% of the population who manifested the symptom of dysphagia presented severe malnutrition already at the first visit, compared to 32% of non-dysphagia subjects. BioMed Central 2021-11-22 /pmc/articles/PMC8607588/ /pubmed/34809654 http://dx.doi.org/10.1186/s12967-021-03144-2 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Cristofaro, Maria Giulia
Barca, Ida
Ferragina, Francesco
Novembre, Daniela
Ferro, Yvelise
Pujia, Roberta
Montalcini, Tiziana
The health risks of dysphagia for patients with head and neck cancer: a multicentre prospective observational study
title The health risks of dysphagia for patients with head and neck cancer: a multicentre prospective observational study
title_full The health risks of dysphagia for patients with head and neck cancer: a multicentre prospective observational study
title_fullStr The health risks of dysphagia for patients with head and neck cancer: a multicentre prospective observational study
title_full_unstemmed The health risks of dysphagia for patients with head and neck cancer: a multicentre prospective observational study
title_short The health risks of dysphagia for patients with head and neck cancer: a multicentre prospective observational study
title_sort health risks of dysphagia for patients with head and neck cancer: a multicentre prospective observational study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607588/
https://www.ncbi.nlm.nih.gov/pubmed/34809654
http://dx.doi.org/10.1186/s12967-021-03144-2
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