A network pharmacology approach to reveal the pharmacological targets and biological mechanism of compound kushen injection for treating pancreatic cancer based on WGCNA and in vitro experiment validation

BACKGROUND: Compound kushen injection (CKI), a Chinese patent drug, is widely used in the treatment of various cancers, especially neoplasms of the digestive system. However, the underlying mechanism of CKI in pancreatic cancer (PC) treatment has not been totally elucidated. METHODS: Here, to overco...

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Detalles Bibliográficos
Autores principales: Wu, Chao, Huang, Zhi-Hong, Meng, Zi-Qi, Fan, Xiao-Tian, Lu, Shan, Tan, Ying-Ying, You, Lei-Ming, Huang, Jia-Qi, Stalin, Antony, Ye, Pei-Zhi, Wu, Zhi-Shan, Zhang, Jing-Yuan, Liu, Xin-Kui, Zhou, Wei, Zhang, Xiao-Meng, Wu, Jia-Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607619/
https://www.ncbi.nlm.nih.gov/pubmed/34809653
http://dx.doi.org/10.1186/s13020-021-00534-y

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