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Temporal dynamics of base excision/single-strand break repair protein complex assembly/disassembly are modulated by the PARP/NAD(+)/SIRT6 axis

Assembly and disassembly of DNA repair protein complexes at DNA damage sites are essential for maintaining genomic integrity. Investigating factors coordinating assembly of the base excision repair (BER) proteins DNA polymerase β (Polβ) and XRCC1 to DNA lesion sites identifies a role for Polβ in reg...

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Detalles Bibliográficos
Autores principales:	Koczor, Christopher A., Saville, Kate M., Andrews, Joel F., Clark, Jennifer, Fang, Qingming, Li, Jianfeng, Al-Rahahleh, Rasha Q., Ibrahim, Md, McClellan, Steven, Makarov, Mikhail V., Migaud, Marie E., Sobol, Robert W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607749/ https://www.ncbi.nlm.nih.gov/pubmed/34731617 http://dx.doi.org/10.1016/j.celrep.2021.109917

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