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BAY 2253651 for the treatment of obstructive sleep apnoea: a multicentre, double-blind, randomised controlled trial (SANDMAN)
BAY 2253651 is a nasally applied genioglossus muscle activator via pharyngeal mucosal receptor stimulation (potassium channel blocker) aimed to treat obstructive sleep apnoea. Although well-tolerated and safe, there was no significant therapeutic effect. https://bit.ly/3zDbyia
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
European Respiratory Society
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607905/ https://www.ncbi.nlm.nih.gov/pubmed/34531274 http://dx.doi.org/10.1183/13993003.01937-2021 |
| _version_ | 1784602654581719040 |
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| author | Gaisl, Thomas Turnbull, Chris D. Weimann, Gerrit Unger, Sigrun Finger, Rudolf Xing, Charles Cistulli, Peter A. West, Sophie Chiang, Alan K.I. Eckert, Danny J. Stradling, John R. Kohler, Malcolm |
| author_facet | Gaisl, Thomas Turnbull, Chris D. Weimann, Gerrit Unger, Sigrun Finger, Rudolf Xing, Charles Cistulli, Peter A. West, Sophie Chiang, Alan K.I. Eckert, Danny J. Stradling, John R. Kohler, Malcolm |
| author_sort | Gaisl, Thomas |
| collection | PubMed |
| description | BAY 2253651 is a nasally applied genioglossus muscle activator via pharyngeal mucosal receptor stimulation (potassium channel blocker) aimed to treat obstructive sleep apnoea. Although well-tolerated and safe, there was no significant therapeutic effect. https://bit.ly/3zDbyia |
| format | Online Article Text |
| id | pubmed-8607905 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | European Respiratory Society |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-86079052021-11-23 BAY 2253651 for the treatment of obstructive sleep apnoea: a multicentre, double-blind, randomised controlled trial (SANDMAN) Gaisl, Thomas Turnbull, Chris D. Weimann, Gerrit Unger, Sigrun Finger, Rudolf Xing, Charles Cistulli, Peter A. West, Sophie Chiang, Alan K.I. Eckert, Danny J. Stradling, John R. Kohler, Malcolm Eur Respir J Agora BAY 2253651 is a nasally applied genioglossus muscle activator via pharyngeal mucosal receptor stimulation (potassium channel blocker) aimed to treat obstructive sleep apnoea. Although well-tolerated and safe, there was no significant therapeutic effect. https://bit.ly/3zDbyia European Respiratory Society 2021-11-18 /pmc/articles/PMC8607905/ /pubmed/34531274 http://dx.doi.org/10.1183/13993003.01937-2021 Text en Copyright ©The authors 2021. https://creativecommons.org/licenses/by-nc/4.0/This version is distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0. For reproduction rights and permissions contact permissions@ersnet.org (mailto:permissions@ersnet.org) |
| spellingShingle | Agora Gaisl, Thomas Turnbull, Chris D. Weimann, Gerrit Unger, Sigrun Finger, Rudolf Xing, Charles Cistulli, Peter A. West, Sophie Chiang, Alan K.I. Eckert, Danny J. Stradling, John R. Kohler, Malcolm BAY 2253651 for the treatment of obstructive sleep apnoea: a multicentre, double-blind, randomised controlled trial (SANDMAN) |
| title | BAY 2253651 for the treatment of obstructive sleep apnoea: a multicentre, double-blind, randomised controlled trial (SANDMAN) |
| title_full | BAY 2253651 for the treatment of obstructive sleep apnoea: a multicentre, double-blind, randomised controlled trial (SANDMAN) |
| title_fullStr | BAY 2253651 for the treatment of obstructive sleep apnoea: a multicentre, double-blind, randomised controlled trial (SANDMAN) |
| title_full_unstemmed | BAY 2253651 for the treatment of obstructive sleep apnoea: a multicentre, double-blind, randomised controlled trial (SANDMAN) |
| title_short | BAY 2253651 for the treatment of obstructive sleep apnoea: a multicentre, double-blind, randomised controlled trial (SANDMAN) |
| title_sort | bay 2253651 for the treatment of obstructive sleep apnoea: a multicentre, double-blind, randomised controlled trial (sandman) |
| topic | Agora |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607905/ https://www.ncbi.nlm.nih.gov/pubmed/34531274 http://dx.doi.org/10.1183/13993003.01937-2021 |
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