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Knock-Down of Heterogeneous Nuclear Ribonucleoprotein A1 Results in Neurite Damage, Altered Stress Granule Biology, and Cellular Toxicity in Differentiated Neuronal Cells
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) is an RNA binding protein (RBP) that is localized within neurons and plays crucial roles in RNA metabolism. Its importance in neuronal functioning is underscored from the study of its pathogenic features in many neurodegenerative diseases where n...
Autores principales: | Anees, Amber, Salapa, Hannah E., Thibault, Patricia A., Hutchinson, Catherine, Hammond, S. Austin, Levin, Michael C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607908/ https://www.ncbi.nlm.nih.gov/pubmed/34697074 http://dx.doi.org/10.1523/ENEURO.0350-21.2021 |
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