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Knock-Down of Heterogeneous Nuclear Ribonucleoprotein A1 Results in Neurite Damage, Altered Stress Granule Biology, and Cellular Toxicity in Differentiated Neuronal Cells

Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) is an RNA binding protein (RBP) that is localized within neurons and plays crucial roles in RNA metabolism. Its importance in neuronal functioning is underscored from the study of its pathogenic features in many neurodegenerative diseases where n...

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Detalles Bibliográficos
Autores principales: Anees, Amber, Salapa, Hannah E., Thibault, Patricia A., Hutchinson, Catherine, Hammond, S. Austin, Levin, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607908/
https://www.ncbi.nlm.nih.gov/pubmed/34697074
http://dx.doi.org/10.1523/ENEURO.0350-21.2021

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