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CCR5 Activation Promotes NLRP1-Dependent Neuronal Pyroptosis via CCR5/PKA/CREB Pathway After Intracerebral Hemorrhage

Neuronal pyroptosis is a type of regulated cell death triggered by proinflammatory signals. CCR5 (C-C chemokine receptor 5)-mediated inflammation is involved in the pathology of various neurological diseases. This study investigated the impact of CCR5 activation on neuronal pyroptosis and the underl...

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Detalles Bibliográficos
Autores principales: Yan, Jun, Xu, Weilin, Lenahan, Cameron, Huang, Lei, Wen, Jing, Li, Gaigai, Hu, Xin, Zheng, Wen, Zhang, John H., Tang, Jiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607924/
https://www.ncbi.nlm.nih.gov/pubmed/34719258
http://dx.doi.org/10.1161/STROKEAHA.120.033285

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