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KRAS A146 Mutations Are Associated With Distinct Clinical Behavior in Patients With Colorectal Liver Metastases

Somatic KRAS mutations occur in approximately half of the patients with metastatic colorectal cancer (mCRC). Biologic tumor characteristics differ on the basis of the KRAS mutation variant. KRAS mutations are known to influence patient prognosis and are used as predictive biomarker for treatment dec...

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Detalles Bibliográficos
Autores principales:	van 't Erve, Iris, Wesdorp, Nina J., Medina, Jamie E., Ferreira, Leonardo, Leal, Alessandro, Huiskens, Joost, Bolhuis, Karen, van Waesberghe, Jan-Hein T. M., Swijnenburg, Rutger-Jan, van den Broek, Daan, Velculescu, Victor E., Kazemier, Geert, Punt, Cornelis J. A., Meijer, Gerrit A., Fijneman, Remond J. A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer Health 2021
Materias:	Original Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608264/ https://www.ncbi.nlm.nih.gov/pubmed/34820593 http://dx.doi.org/10.1200/PO.21.00223

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