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Novel Circulating Hypermethylated RASSF1A ddPCR for Liquid Biopsies in Patients With Pediatric Solid Tumors

Liquid biopsies can be used to investigate tumor-derived DNA, circulating in the cell-free DNA (cfDNA) pool in blood. We aimed to develop a droplet digital polymerase chain reaction (ddPCR) assay detecting hypermethylation of tumor suppressor gene RASSF1A as a simple standard test to detect various...

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Detalles Bibliográficos
Autores principales:	van Zogchel, Lieke M. J., Lak, Nathalie S. M., Verhagen, Onno J. H. M., Tissoudali, Ahmed, Gussmalla Nuru, Mohammed, Gelineau, Nina U., Zappeij-Kannengieter, Lily, Javadi, Ahmad, Zijtregtop, Eline A. M., Merks, Johannes H. M., van den Heuvel-Eibrink, Marry, Schouten-van Meeteren, Antoinette Y. N., Stutterheim, Janine, van der Schoot, C. Ellen, Tytgat, Godelieve A. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer Health 2021
Materias:	Original Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608265/ https://www.ncbi.nlm.nih.gov/pubmed/34820594 http://dx.doi.org/10.1200/PO.21.00130

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