A Case Report of Steroid-Resistant Cryptogenic Organizing Pneumonia Managed with Intravenous Immunoglobulins

Fewer than ten reported cases of cryptogenic organizing pneumonia (COP) have been managed with intravenous immunoglobulins (IVIg). We report a case of a 72-year-old man who presented with a worsening cough and diffuse opacities on chest radiograph. Following no improvement with antibiotics and negat...

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Autores principales: Dimala, Christian Akem, Patel, Urvi, Lloyd, Benjamin, Donato, Anthony, Kimmel, William B., Hallowell, Robert, Moss, Caitlyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608529/
https://www.ncbi.nlm.nih.gov/pubmed/34820143
http://dx.doi.org/10.1155/2021/9343491
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author Dimala, Christian Akem
Patel, Urvi
Lloyd, Benjamin
Donato, Anthony
Kimmel, William B.
Hallowell, Robert
Moss, Caitlyn
author_facet Dimala, Christian Akem
Patel, Urvi
Lloyd, Benjamin
Donato, Anthony
Kimmel, William B.
Hallowell, Robert
Moss, Caitlyn
author_sort Dimala, Christian Akem
collection PubMed
description Fewer than ten reported cases of cryptogenic organizing pneumonia (COP) have been managed with intravenous immunoglobulins (IVIg). We report a case of a 72-year-old man who presented with a worsening cough and diffuse opacities on chest radiograph. Following no improvement with antibiotics and negative complementary investigations for infectious, malignant, and autoimmune etiologies, COP was confirmed on lung biopsy. Due to continued clinical deterioration despite high-dose steroids and new severe steroid-induced hallucinations, the patient was placed on intravenous immunoglobulins (IVIg) and mycophenolate mofetil and made a satisfactory recovery. IVIg should be considered as an important steroid-sparing alternative in patients with COP.
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spelling pubmed-86085292021-11-23 A Case Report of Steroid-Resistant Cryptogenic Organizing Pneumonia Managed with Intravenous Immunoglobulins Dimala, Christian Akem Patel, Urvi Lloyd, Benjamin Donato, Anthony Kimmel, William B. Hallowell, Robert Moss, Caitlyn Case Rep Pulmonol Case Report Fewer than ten reported cases of cryptogenic organizing pneumonia (COP) have been managed with intravenous immunoglobulins (IVIg). We report a case of a 72-year-old man who presented with a worsening cough and diffuse opacities on chest radiograph. Following no improvement with antibiotics and negative complementary investigations for infectious, malignant, and autoimmune etiologies, COP was confirmed on lung biopsy. Due to continued clinical deterioration despite high-dose steroids and new severe steroid-induced hallucinations, the patient was placed on intravenous immunoglobulins (IVIg) and mycophenolate mofetil and made a satisfactory recovery. IVIg should be considered as an important steroid-sparing alternative in patients with COP. Hindawi 2021-11-15 /pmc/articles/PMC8608529/ /pubmed/34820143 http://dx.doi.org/10.1155/2021/9343491 Text en Copyright © 2021 Christian Akem Dimala et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Dimala, Christian Akem
Patel, Urvi
Lloyd, Benjamin
Donato, Anthony
Kimmel, William B.
Hallowell, Robert
Moss, Caitlyn
A Case Report of Steroid-Resistant Cryptogenic Organizing Pneumonia Managed with Intravenous Immunoglobulins
title A Case Report of Steroid-Resistant Cryptogenic Organizing Pneumonia Managed with Intravenous Immunoglobulins
title_full A Case Report of Steroid-Resistant Cryptogenic Organizing Pneumonia Managed with Intravenous Immunoglobulins
title_fullStr A Case Report of Steroid-Resistant Cryptogenic Organizing Pneumonia Managed with Intravenous Immunoglobulins
title_full_unstemmed A Case Report of Steroid-Resistant Cryptogenic Organizing Pneumonia Managed with Intravenous Immunoglobulins
title_short A Case Report of Steroid-Resistant Cryptogenic Organizing Pneumonia Managed with Intravenous Immunoglobulins
title_sort case report of steroid-resistant cryptogenic organizing pneumonia managed with intravenous immunoglobulins
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608529/
https://www.ncbi.nlm.nih.gov/pubmed/34820143
http://dx.doi.org/10.1155/2021/9343491
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