Genetically edited hepatic cells expressing the NTCP-S267F variant are resistant to hepatitis B virus infection

The sodium-dependent taurocholate co-transporting polypeptide (NTCP)-S267F variant is known to be associated with a reduced risk of hepatitis B virus (HBV) infection and disease progression. The NTCP-S267F variant displays diminished function in mediating HBV entry, but its function in HBV infection...

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Detalles Bibliográficos
Autores principales: Uchida, Takuro, Park, Seung Bum, Inuzuka, Tadashi, Zhang, Min, Allen, Joselyn N., Chayama, Kazuaki, Liang, T. Jake
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608598/
https://www.ncbi.nlm.nih.gov/pubmed/34853804
http://dx.doi.org/10.1016/j.omtm.2021.11.002

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