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Methodology for clinical genotyping of CYP2D6 and CYP2C19

Many antidepressants, atomoxetine, and several antipsychotics are metabolized by the cytochrome P450 enzymes CYP2D6 and CYP2C19, and guidelines for prescribers based on genetic variants exist. Although some laboratories offer such testing, there is no consensus regarding validated methodology for cl...

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Detalles Bibliográficos
Autores principales:	Carvalho Henriques, Beatriz, Buchner, Avery, Hu, Xiuying, Wang, Yabing, Yavorskyy, Vasyl, Wallace, Keanna, Dong, Rachael, Martens, Kristina, Carr, Michael S., Behroozi Asl, Bahareh, Hague, Joshua, Sivapalan, Sudhakar, Maier, Wolfgang, Dernovsek, Mojca Z., Henigsberg, Neven, Hauser, Joanna, Souery, Daniel, Cattaneo, Annamaria, Mors, Ole, Rietschel, Marcella, Pfeffer, Gerald, Hume, Stacey, Aitchison, Katherine J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608805/ https://www.ncbi.nlm.nih.gov/pubmed/34811360 http://dx.doi.org/10.1038/s41398-021-01717-9

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