Betulinic Acid Hydroxamate is Neuroprotective and Induces Protein Phosphatase 2A-Dependent HIF-1α Stabilization and Post-transcriptional Dephosphorylation of Prolyl Hydrolase 2

Huntington’s disease (HD) is a neurodegenerative disorder characterized by unwanted choreatic movements, behavioral and psychiatric disturbances, and dementia. The activation of the hypoxic response pathway through the pharmacological inhibition of hypoxia-inducing factor (HIF) prolyl-hydroxylases (...

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Detalles Bibliográficos
Autores principales: Prados, María E., Correa-Sáez, Alejandro, Unciti-Broceta, Juan D., Garrido-Rodríguez, Martín, Jimenez-Jimenez, Carla, Mazzone, Massimiliano, Minassi, Alberto, Appendino, Giovanni, Calzado, Marco A., Muñoz, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608974/
https://www.ncbi.nlm.nih.gov/pubmed/34339019
http://dx.doi.org/10.1007/s13311-021-01089-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608974/
https://www.ncbi.nlm.nih.gov/pubmed/34339019
http://dx.doi.org/10.1007/s13311-021-01089-4

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