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Betulinic Acid Hydroxamate is Neuroprotective and Induces Protein Phosphatase 2A-Dependent HIF-1α Stabilization and Post-transcriptional Dephosphorylation of Prolyl Hydrolase 2

Huntington’s disease (HD) is a neurodegenerative disorder characterized by unwanted choreatic movements, behavioral and psychiatric disturbances, and dementia. The activation of the hypoxic response pathway through the pharmacological inhibition of hypoxia-inducing factor (HIF) prolyl-hydroxylases (...

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Detalles Bibliográficos
Autores principales:	Prados, María E., Correa-Sáez, Alejandro, Unciti-Broceta, Juan D., Garrido-Rodríguez, Martín, Jimenez-Jimenez, Carla, Mazzone, Massimiliano, Minassi, Alberto, Appendino, Giovanni, Calzado, Marco A., Muñoz, Eduardo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608974/ https://www.ncbi.nlm.nih.gov/pubmed/34339019 http://dx.doi.org/10.1007/s13311-021-01089-4

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