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Comparative validation of three DNA methylation algorithms of ageing and a frailty index in relation to mortality: results from the ESTHER cohort study

BACKGROUND: Three DNA methylation (DNAm) based algorithms, DNAm PhenoAge acceleration (AgeAccelPheno), DNAm GrimAge acceleration (AgeAccelGrim), and mortality risk score (MRscore), based on methylation in 513, 1030, and 10 CpGs, respectively, were established to predict health outcomes and mortality...

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Detalles Bibliográficos
Autores principales:	Li, Xiangwei, Zhang, Yan, Gào, Xīn, Holleczek, Bernd, Schöttker, Ben, Brenner, Hermann
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Research paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609015/ https://www.ncbi.nlm.nih.gov/pubmed/34808433 http://dx.doi.org/10.1016/j.ebiom.2021.103686

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