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FRET-Based Screening Identifies p38 MAPK and PKC Inhibition as Targets for Prevention of Seeded α-Synuclein Aggregation

Aggregation of α-synuclein is associated with neurodegeneration and a hallmark pathology in synucleinopathies. These aggregates are thought to function as prion-like particles where the conformation of misfolded α-synuclein determines the traits of the induced pathology, similar to prion diseases. S...

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Detalles Bibliográficos
Autores principales:	Svanbergsson, Alexander, Ek, Fredrik, Martinsson, Isak, Rodo, Jordi, Liu, Di, Brandi, Edoardo, Haikal, Caroline, Torres-Garcia, Laura, Li, Wen, Gouras, Gunnar, Olsson, Roger, Björklund, Tomas, Li, Jia-Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609038/ https://www.ncbi.nlm.nih.gov/pubmed/34258749 http://dx.doi.org/10.1007/s13311-021-01070-1

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