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The roles and mechanisms of the m6A reader protein YTHDF1 in tumor biology and human diseases

YTHDF1 is the most versatile and powerful reader protein of N(6)-methyladenosine (m6A)-modified RNA, and it can recognize both G(m6A)C and A(m6A)C RNAs as ligands without sequence selectivity. YTHDF1 regulates target gene expression by different mechanisms, such as promoting translation or regulatin...

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Detalles Bibliográficos
Autores principales: Chen, Zuyao, Zhong, Xiaolin, Xia, Min, Zhong, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609105/
https://www.ncbi.nlm.nih.gov/pubmed/34853726
http://dx.doi.org/10.1016/j.omtn.2021.10.023