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The roles and mechanisms of the m6A reader protein YTHDF1 in tumor biology and human diseases
YTHDF1 is the most versatile and powerful reader protein of N(6)-methyladenosine (m6A)-modified RNA, and it can recognize both G(m6A)C and A(m6A)C RNAs as ligands without sequence selectivity. YTHDF1 regulates target gene expression by different mechanisms, such as promoting translation or regulatin...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609105/ https://www.ncbi.nlm.nih.gov/pubmed/34853726 http://dx.doi.org/10.1016/j.omtn.2021.10.023 |