Full-length transcript sequencing of human and mouse cerebral cortex identifies widespread isoform diversity and alternative splicing

Alternative splicing is a post-transcriptional regulatory mechanism producing distinct mRNA molecules from a single pre-mRNA with a prominent role in the development and function of the central nervous system. We used long-read isoform sequencing to generate full-length transcript sequences in the h...

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Detalles Bibliográficos
Autores principales: Leung, Szi Kay, Jeffries, Aaron R., Castanho, Isabel, Jordan, Ben T., Moore, Karen, Davies, Jonathan P., Dempster, Emma L., Bray, Nicholas J., O’Neill, Paul, Tseng, Elizabeth, Ahmed, Zeshan, Collier, David A., Jeffery, Erin D., Prabhakar, Shyam, Schalkwyk, Leonard, Jops, Connor, Gandal, Michael J., Sheynkman, Gloria M., Hannon, Eilis, Mill, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609283/
https://www.ncbi.nlm.nih.gov/pubmed/34788620
http://dx.doi.org/10.1016/j.celrep.2021.110022

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