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Neuronal Deposition of Amyloid-β Oligomers and Hyperphosphorylated Tau Is Closely Connected with Cognitive Dysfunction in Aged Dogs

BACKGROUND: Canine cognitive dysfunction (CCD) is a progressive syndrome recognized in mature to aged dogs with a variety of neuropathological changes similar to human Alzheimer’s disease (AD), for which it is thought to be a good natural model. However, the presence of hyperphosphorylated tau prote...

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Detalles Bibliográficos
Autores principales:	Habiba, Umma, Ozawa, Makiko, Chambers, James K., Uchida, Kazuyuki, Descallar, Joseph, Nakayama, Hiroyuki, Summers, Brian A., Morley, John W., Tayebi, Mourad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2021
Materias:	Research Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609497/ https://www.ncbi.nlm.nih.gov/pubmed/34870101 http://dx.doi.org/10.3233/ADR-210035

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