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GenoChemetic Strategy for Derivatization of the Violacein Natural Product Scaffold

[Image: see text] Natural products and their analogues are often challenging to synthesize due to their complex scaffolds and embedded functional groups. Solely relying on engineering the biosynthesis of natural products may lead to limited compound diversity. Integrating synthetic biology with synt...

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Detalles Bibliográficos
Autores principales: Lai, Hung-En, Obled, Alan M. C., Chee, Soo Mei, Morgan, Rhodri M., Lynch, Rosemary, Sharma, Sunil V., Moore, Simon J., Polizzi, Karen M., Goss, Rebecca J. M., Freemont, Paul S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609527/
https://www.ncbi.nlm.nih.gov/pubmed/34648268
http://dx.doi.org/10.1021/acschembio.1c00483