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Rational prioritization strategy allows the design of macrolide derivatives that overcome antibiotic resistance
Antibiotic resistance is a major threat to global health; this problem can be addressed by the development of new antibacterial agents to keep pace with the evolutionary adaptation of pathogens. Computational approaches are essential tools to this end since their application enables fast and early s...
| Autores principales: | , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609559/ https://www.ncbi.nlm.nih.gov/pubmed/34750269 http://dx.doi.org/10.1073/pnas.2113632118 |