Proceedings of the Sleep and Epilepsy Workshop: Section 3 Mortality: Sleep, Night, and SUDEP

Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death in patients with refractory epilepsy. Likely pathophysiological mechanisms include seizure-induced cardiac and respiratory dysregulation. A frequently identified feature in SUDEP cases is that they occur at night. This raises...

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Autores principales: Buchanan, Gordon F., Gluckman, Bruce J., Kalume, Franck K., Lhatoo, Samden, Maganti, Rama K., Noebels, Jeffrey L., Simeone, Kristina A., Quigg, Mark S., Pavlova, Milena K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Proceedings of the Sleep and Epilepsy Workshop
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609595/
https://www.ncbi.nlm.nih.gov/pubmed/33787378
http://dx.doi.org/10.1177/15357597211004556
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author Buchanan, Gordon F.
Gluckman, Bruce J.
Kalume, Franck K.
Lhatoo, Samden
Maganti, Rama K.
Noebels, Jeffrey L.
Simeone, Kristina A.
Quigg, Mark S.
Pavlova, Milena K.
author_facet Buchanan, Gordon F.
Gluckman, Bruce J.
Kalume, Franck K.
Lhatoo, Samden
Maganti, Rama K.
Noebels, Jeffrey L.
Simeone, Kristina A.
Quigg, Mark S.
Pavlova, Milena K.
author_sort Buchanan, Gordon F.
collection PubMed
description Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death in patients with refractory epilepsy. Likely pathophysiological mechanisms include seizure-induced cardiac and respiratory dysregulation. A frequently identified feature in SUDEP cases is that they occur at night. This raises the question of a role for sleep state in regulating of SUDEP. An association with sleep has been identified in a number of studies with patients and in animal models. The focus of this section of the Sleep and Epilepsy Workshop was on identifying and understanding the role for sleep and time of day in the pathophysiology of SUDEP.
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spelling pubmed-86095952021-12-02 Proceedings of the Sleep and Epilepsy Workshop: Section 3 Mortality: Sleep, Night, and SUDEP Buchanan, Gordon F. Gluckman, Bruce J. Kalume, Franck K. Lhatoo, Samden Maganti, Rama K. Noebels, Jeffrey L. Simeone, Kristina A. Quigg, Mark S. Pavlova, Milena K. Epilepsy Curr Proceedings of the Sleep and Epilepsy Workshop Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death in patients with refractory epilepsy. Likely pathophysiological mechanisms include seizure-induced cardiac and respiratory dysregulation. A frequently identified feature in SUDEP cases is that they occur at night. This raises the question of a role for sleep state in regulating of SUDEP. An association with sleep has been identified in a number of studies with patients and in animal models. The focus of this section of the Sleep and Epilepsy Workshop was on identifying and understanding the role for sleep and time of day in the pathophysiology of SUDEP. SAGE Publications 2021-03-31 /pmc/articles/PMC8609595/ /pubmed/33787378 http://dx.doi.org/10.1177/15357597211004556 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Proceedings of the Sleep and Epilepsy Workshop
Buchanan, Gordon F.
Gluckman, Bruce J.
Kalume, Franck K.
Lhatoo, Samden
Maganti, Rama K.
Noebels, Jeffrey L.
Simeone, Kristina A.
Quigg, Mark S.
Pavlova, Milena K.
Proceedings of the Sleep and Epilepsy Workshop: Section 3 Mortality: Sleep, Night, and SUDEP
title Proceedings of the Sleep and Epilepsy Workshop: Section 3 Mortality: Sleep, Night, and SUDEP
title_full Proceedings of the Sleep and Epilepsy Workshop: Section 3 Mortality: Sleep, Night, and SUDEP
title_fullStr Proceedings of the Sleep and Epilepsy Workshop: Section 3 Mortality: Sleep, Night, and SUDEP
title_full_unstemmed Proceedings of the Sleep and Epilepsy Workshop: Section 3 Mortality: Sleep, Night, and SUDEP
title_short Proceedings of the Sleep and Epilepsy Workshop: Section 3 Mortality: Sleep, Night, and SUDEP
title_sort proceedings of the sleep and epilepsy workshop: section 3 mortality: sleep, night, and sudep
topic Proceedings of the Sleep and Epilepsy Workshop
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609595/
https://www.ncbi.nlm.nih.gov/pubmed/33787378
http://dx.doi.org/10.1177/15357597211004556
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