Preferential and persistent impact of acute HIV-1 infection on CD4(+) iNKT cells in colonic mucosa

Acute HIV-1 infection (AHI) results in the widespread depletion of CD4(+) T cells in peripheral blood and gut mucosal tissue. However, the impact on the predominantly CD4(+) immunoregulatory invariant natural killer T (iNKT) cells during AHI remains unknown. Here, iNKT cells from peripheral blood an...

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Detalles Bibliográficos
Autores principales: Paquin-Proulx, Dominic, Lal, Kerri G., Phuang-Ngern, Yuwadee, Creegan, Matthew, Tokarev, Andrey, Suhkumvittaya, Suchada, Alrubayyi, Aljawharah, Kroon, Eugène, Pinyakorn, Suteeraporn, Slike, Bonnie M., Bolton, Diane L., Krebs, Shelly J., Eller, Leigh Anne, Sajjaweerawan, Chayada, Pagliuzza, Amélie, Chomont, Nicolas, Rerknimitr, Rungsun, Chomchey, Nitiya, Phanuphak, Nittaya, de Souza, Mark S., Michael, Nelson L., Robb, Merlin L., Ananworanich, Jintanat, Sandberg, Johan K., Eller, Michael A., Schuetz, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609642/
https://www.ncbi.nlm.nih.gov/pubmed/34753817
http://dx.doi.org/10.1073/pnas.2104721118

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