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Assessing Genetic Overlap and Causality Between Blood Plasma Proteins and Alzheimer’s Disease

BACKGROUND: Blood plasma proteins have been associated with Alzheimer’s disease (AD), but understanding which proteins are on the causal pathway remains challenging. OBJECTIVE: Investigate the genetic overlap between candidate proteins and AD using polygenic risk scores (PRS) and interrogate their c...

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Detalles Bibliográficos
Autores principales:	Handy, Alex, Lord, Jodie, Green, Rebecca, Xu, Jin, Aarsland, Dag, Velayudhan, Latha, Hye, Abdul, Dobson, Richard, Proitsi, Petroula
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609677/ https://www.ncbi.nlm.nih.gov/pubmed/34459398 http://dx.doi.org/10.3233/JAD-210462

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