Cargando…

Locus Coeruleus Degeneration Correlated with Levodopa Resistance in Parkinson’s Disease: A Retrospective Analysis

BACKGROUND: The widely divergent responsiveness of Parkinson’s disease (PD) patients to levodopa is an important clinical issue because of its relationship with quality of life and disease prognosis. Preliminary animal experiments have suggested that degeneration of the locus coeruleus (LC) attenuat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Cheng, Guo, Tao, Wu, JingJing, Wang, Linbo, Bai, Xueqin, Gao, Ting, Guan, Xiaojun, Gu, Luyan, Huang, Peiyu, Xuan, Min, Gu, Quanquan, Xu, Xiaojun, Zhang, Baorong, Cheng, Wei, Feng, Jianfeng, Zhang, Minming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2021
Materias:	Research Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609680/ https://www.ncbi.nlm.nih.gov/pubmed/34366373 http://dx.doi.org/10.3233/JPD-212720

Ejemplares similares

Locus coeruleus degeneration is associated with disorganized functional topology in Parkinson’s disease
por: Zhou, Cheng, et al.
Publicado: (2021)

Normalization effect of levodopa on hierarchical brain function in Parkinson’s disease
por: Guo, Tao, et al.
Publicado: (2022)

Genetic impacts on nigral iron deposition in Parkinson's disease: A preliminary quantitative susceptibility mapping study
por: Wu, Jingjing, et al.
Publicado: (2023)

Microstructural but not macrostructural cortical degeneration occurs in Parkinson’s disease with mild cognitive impairment
por: Bai, Xueqin, et al.
Publicado: (2022)

Cholinergic relevant functional reactivity is associated with dopamine responsiveness of tremor in Parkinson’s disease
por: Wu, Jingjing, et al.
Publicado: (2022)

Damaged Insula Network Contributes to Depression in Parkinson’s Disease
por: Huang, Peiyu, et al.
Publicado: (2020)

Identifying a whole‐brain connectome‐based model in drug‐naïve Parkinson's disease for predicting motor impairment
por: Wu, Haoting, et al.
Publicado: (2021)

Dopamine depletion and subcortical dysfunction disrupt cortical synchronization and metastability affecting cognitive function in Parkinson's disease
por: Wang, Linbo, et al.
Publicado: (2021)

Two distinct trajectories of clinical and neurodegeneration events in Parkinson’s disease
por: Zhou, Cheng, et al.
Publicado: (2023)

Clinically relevant connectivity features define three subtypes of Parkinson's disease patients
por: Guo, Tao, et al.
Publicado: (2020)

Longitudinal Macro/Microstructural Alterations of Different Callosal Subsections in Parkinson’s Disease Using Connectivity-Based Parcellation
por: Wu, Jingjing, et al.
Publicado: (2020)

Functional connectomes of akinetic‐rigid and tremor within drug‐naïve Parkinson's disease
por: Wu, Haoting, et al.
Publicado: (2023)

Brain Atrophy and Reorganization of Structural Network in Parkinson's Disease With Hemiparkinsonism
por: Xu, Xiaojun, et al.
Publicado: (2018)

Alterations of Brain Structural Network in Parkinson’s Disease With and Without Rapid Eye Movement Sleep Behavior Disorder
por: Guo, Tao, et al.
Publicado: (2018)

Asymmetrical nigral iron accumulation in Parkinson’s disease with motor asymmetry: an explorative, longitudinal and test-retest study
por: Guan, Xiaojun, et al.
Publicado: (2020)

Nigral Iron Deposition Influences Disease Severity by Modulating the Effect of Parkinson’s Disease on Brain Networks
por: Wen, Jiaqi, et al.
Publicado: (2022)

Structural Covariance Network Disruption and Functional Compensation in Parkinson’s Disease
por: Zhou, Cheng, et al.
Publicado: (2020)

Regional white matter hyperintensity volume in Parkinson's disease and associations with the motor signs
por: Wu, Haoting, et al.
Publicado: (2023)

Disrupted Functional Connectivity of Basal Ganglia across Tremor-Dominant and Akinetic/Rigid-Dominant Parkinson’s Disease
por: Guan, Xiaojun, et al.
Publicado: (2017)

Fixel-based analysis reveals fiber-specific alterations during the progression of Parkinson’s disease
por: Li, Yanxuan, et al.
Publicado: (2020)

Gray and white matter alterations in different predominant side and type of motor symptom in Parkinson's disease
por: Chen, Jingwen, et al.
Publicado: (2022)

Increased thalamic centrality and putamen–thalamic connectivity in patients with parkinsonian resting tremor
por: Gu, Quanquan, et al.
Publicado: (2016)

Automatic Classification of Early Parkinson's Disease with Multi-Modal MR Imaging
por: Long, Dan, et al.
Publicado: (2012)

Oscillation-specific nodal alterations in early to middle stages Parkinson’s disease
por: Guan, Xiaojun, et al.
Publicado: (2019)

A role for locus coeruleus in Parkinson tremor
por: Isaias, Ioannis U., et al.
Publicado: (2012)

Locus Coeruleus Modulates Neuroinflammation in Parkinsonism and Dementia
por: Giorgi, Filippo Sean, et al.
Publicado: (2020)

Locus Coeruleus Degeneration Differs Between Frontotemporal Lobar Degeneration Subtypes
por: Matti, Nathalie, et al.
Publicado: (2022)

Neuroimaging evidence of glymphatic system dysfunction in possible REM sleep behavior disorder and Parkinson’s disease
por: Si, Xiaoli, et al.
Publicado: (2022)

Altered Cortical Cholinergic Network in Parkinson’s Disease at Different Stage: A Resting-State fMRI Study
por: Sheng, Wenshuang, et al.
Publicado: (2021)

Disruption of locus coeruleus-related functional networks in Parkinson’s disease
por: Sun, Junyan, et al.
Publicado: (2023)

Association between cigarette smoking and Parkinson’s disease: a neuroimaging study
por: Wang, Chao, et al.
Publicado: (2022)

Normalization effect of dopamine replacement therapy on brain functional connectome in Parkinson's disease
por: Wu, Chenqing, et al.
Publicado: (2023)

Locus Coeruleus atrophy doesn’t relate to fatigue in Parkinson’s disease
por: Solopchuk, Oleg, et al.
Publicado: (2018)

Locus coeruleus-norepinephrine: basic functions and insights into Parkinson’s disease
por: Bari, Bilal Abdul, et al.
Publicado: (2019)

Noradrenergic pathway from the locus coeruleus to heart is implicated in modulating SUDEP
por: Lian, XiTing, et al.
Publicado: (2023)

Altered spontaneous brain activity in chronic smokers revealed by fractional ramplitude of low-frequency fluctuation analysis: a preliminary study
por: Wang, Chao, et al.
Publicado: (2017)

The Contribution of the Locus Coeruleus–Noradrenaline System Degeneration during the Progression of Alzheimer’s Disease
por: Mercan, Dilek, et al.
Publicado: (2022)

Locus coeruleus integrity and the effect of atomoxetine on response inhibition in Parkinson’s disease
por: O’Callaghan, Claire, et al.
Publicado: (2021)

Association of coffee consumption and striatal volume in patients with Parkinson's disease and healthy controls
por: Wang, Chao, et al.
Publicado: (2023)

Differential vulnerability of locus coeruleus and dorsal raphe neurons to chronic methamphetamine-induced degeneration
por: Du, Yijuan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_39hoa3tii1sasqokifou7rtous