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Age-Dependent Degradation of Locomotion Encoding in Huntington’s Disease R6/2 Model Mice
BACKGROUND: Huntington’s disease (HD) is an inherited fatal neurodegenerative disease, leading to neocortical and striatal atrophy. The commonly studied R6/2 HD transgenic mouse model displays progressive motor and cognitive deficits in parallel to major pathological changes in corticostriatal circu...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609681/ https://www.ncbi.nlm.nih.gov/pubmed/34420979 http://dx.doi.org/10.3233/JHD-210492 |