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Age-Dependent Degradation of Locomotion Encoding in Huntington’s Disease R6/2 Model Mice

BACKGROUND: Huntington’s disease (HD) is an inherited fatal neurodegenerative disease, leading to neocortical and striatal atrophy. The commonly studied R6/2 HD transgenic mouse model displays progressive motor and cognitive deficits in parallel to major pathological changes in corticostriatal circu...

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Detalles Bibliográficos
Autores principales:	Yamin, Hagar G., Menkes-Caspi, Noa, Stern, Edward A., Cohen, Dana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2021
Materias:	Research Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609681/ https://www.ncbi.nlm.nih.gov/pubmed/34420979 http://dx.doi.org/10.3233/JHD-210492

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