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Characteristics of in-hospital mortality of congenital heart disease (CHD) after surgical treatment in children from 2005 to 2017: a single-center experience

BACKGROUND: To evaluate trends in the in-hospital mortality rate for pediatric cardiac surgery procedures between 2005 and 2017 in our center, and to discuss the mortality characteristics of children’s CHD after thoracotomy. METHODS: This retrospective data were collected from medical records of chi...

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Autores principales: Zheng, Guilang, Wu, Jiaxing, Chen, Peiling, Hu, Yan, Zhang, Huiqiong, Wang, Jing, Zeng, Hanshi, Li, Xufeng, Sun, Yueyu, Xu, Gang, Wen, Shusheng, Cen, Jianzheng, Chen, Jimei, Guo, Yuxiong, Zhuang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609813/
https://www.ncbi.nlm.nih.gov/pubmed/34814864
http://dx.doi.org/10.1186/s12887-021-02935-2
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author Zheng, Guilang
Wu, Jiaxing
Chen, Peiling
Hu, Yan
Zhang, Huiqiong
Wang, Jing
Zeng, Hanshi
Li, Xufeng
Sun, Yueyu
Xu, Gang
Wen, Shusheng
Cen, Jianzheng
Chen, Jimei
Guo, Yuxiong
Zhuang, Jian
author_facet Zheng, Guilang
Wu, Jiaxing
Chen, Peiling
Hu, Yan
Zhang, Huiqiong
Wang, Jing
Zeng, Hanshi
Li, Xufeng
Sun, Yueyu
Xu, Gang
Wen, Shusheng
Cen, Jianzheng
Chen, Jimei
Guo, Yuxiong
Zhuang, Jian
author_sort Zheng, Guilang
collection PubMed
description BACKGROUND: To evaluate trends in the in-hospital mortality rate for pediatric cardiac surgery procedures between 2005 and 2017 in our center, and to discuss the mortality characteristics of children’s CHD after thoracotomy. METHODS: This retrospective data were collected from medical records of children underwent CHD surgery between 2005 and 2017. RESULTS: A total of 19,114 children with CHD underwent surgery and 444 children died, with the in-hospital mortality was 2.3%. Complex mixed defect CHD had the highest fatality rate (8.63%), left obstructive lesion CHD had the second highest fatality rate (4.49%), right to left shunt CHD had the third highest mortality rate (3.51%), left to right shunt CHD had the lowest mortality rate (χ2 = 520.3,P < 0.05). The neonatal period has the highest mortality rate (12.17%), followed by infant mortality (2.58%), toddler age mortality (1.16%), and preschool age mortality (0.94%), the school age and adolescent mortality rate was the lowest (χ2 = 529.3,P < 0.05). In addition, the fatality rate in boys was significantly higher than that in girls (2.77% versus 1.62%, χ2 = 26.4, P < 0.05). CONCLUSIONS: The mortality rate of CHD surgery in children decreased year by year. The younger the age and the more complicated the cyanotic heart disease, the higher the mortality rate may be.
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spelling pubmed-86098132021-11-29 Characteristics of in-hospital mortality of congenital heart disease (CHD) after surgical treatment in children from 2005 to 2017: a single-center experience Zheng, Guilang Wu, Jiaxing Chen, Peiling Hu, Yan Zhang, Huiqiong Wang, Jing Zeng, Hanshi Li, Xufeng Sun, Yueyu Xu, Gang Wen, Shusheng Cen, Jianzheng Chen, Jimei Guo, Yuxiong Zhuang, Jian BMC Pediatr Research BACKGROUND: To evaluate trends in the in-hospital mortality rate for pediatric cardiac surgery procedures between 2005 and 2017 in our center, and to discuss the mortality characteristics of children’s CHD after thoracotomy. METHODS: This retrospective data were collected from medical records of children underwent CHD surgery between 2005 and 2017. RESULTS: A total of 19,114 children with CHD underwent surgery and 444 children died, with the in-hospital mortality was 2.3%. Complex mixed defect CHD had the highest fatality rate (8.63%), left obstructive lesion CHD had the second highest fatality rate (4.49%), right to left shunt CHD had the third highest mortality rate (3.51%), left to right shunt CHD had the lowest mortality rate (χ2 = 520.3,P < 0.05). The neonatal period has the highest mortality rate (12.17%), followed by infant mortality (2.58%), toddler age mortality (1.16%), and preschool age mortality (0.94%), the school age and adolescent mortality rate was the lowest (χ2 = 529.3,P < 0.05). In addition, the fatality rate in boys was significantly higher than that in girls (2.77% versus 1.62%, χ2 = 26.4, P < 0.05). CONCLUSIONS: The mortality rate of CHD surgery in children decreased year by year. The younger the age and the more complicated the cyanotic heart disease, the higher the mortality rate may be. BioMed Central 2021-11-23 /pmc/articles/PMC8609813/ /pubmed/34814864 http://dx.doi.org/10.1186/s12887-021-02935-2 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Zheng, Guilang
Wu, Jiaxing
Chen, Peiling
Hu, Yan
Zhang, Huiqiong
Wang, Jing
Zeng, Hanshi
Li, Xufeng
Sun, Yueyu
Xu, Gang
Wen, Shusheng
Cen, Jianzheng
Chen, Jimei
Guo, Yuxiong
Zhuang, Jian
Characteristics of in-hospital mortality of congenital heart disease (CHD) after surgical treatment in children from 2005 to 2017: a single-center experience
title Characteristics of in-hospital mortality of congenital heart disease (CHD) after surgical treatment in children from 2005 to 2017: a single-center experience
title_full Characteristics of in-hospital mortality of congenital heart disease (CHD) after surgical treatment in children from 2005 to 2017: a single-center experience
title_fullStr Characteristics of in-hospital mortality of congenital heart disease (CHD) after surgical treatment in children from 2005 to 2017: a single-center experience
title_full_unstemmed Characteristics of in-hospital mortality of congenital heart disease (CHD) after surgical treatment in children from 2005 to 2017: a single-center experience
title_short Characteristics of in-hospital mortality of congenital heart disease (CHD) after surgical treatment in children from 2005 to 2017: a single-center experience
title_sort characteristics of in-hospital mortality of congenital heart disease (chd) after surgical treatment in children from 2005 to 2017: a single-center experience
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609813/
https://www.ncbi.nlm.nih.gov/pubmed/34814864
http://dx.doi.org/10.1186/s12887-021-02935-2
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