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Evaluating dopamine transporter imaging as an enrichment biomarker in a phase 2 Parkinson’s disease trial
BACKGROUND: Dopamine transporter single-photon emission computed tomography (DaT-SPECT) can quantify the functional integrity of the dopaminergic nerve terminals and has been suggested as an imaging modality to verify the clinical diagnosis of Parkinson’s disease (PD). Depending on the stage of prog...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609885/ https://www.ncbi.nlm.nih.gov/pubmed/34814867 http://dx.doi.org/10.1186/s12883-021-02470-8 |