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Evaluating dopamine transporter imaging as an enrichment biomarker in a phase 2 Parkinson’s disease trial

BACKGROUND: Dopamine transporter single-photon emission computed tomography (DaT-SPECT) can quantify the functional integrity of the dopaminergic nerve terminals and has been suggested as an imaging modality to verify the clinical diagnosis of Parkinson’s disease (PD). Depending on the stage of prog...

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Detalles Bibliográficos
Autores principales:	Hutchison, R. Matthew, Evans, Karleyton C., Fox, Tara, Yang, Minhua, Barakos, Jerome, Bedell, Barry J., Cedarbaum, Jesse M., Brys, Miroslaw, Siderowf, Andrew, Lang, Anthony E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609885/ https://www.ncbi.nlm.nih.gov/pubmed/34814867 http://dx.doi.org/10.1186/s12883-021-02470-8

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