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The evolution of the metazoan Toll receptor family and its expression during protostome development

BACKGROUND: Toll-like receptors (TLRs) play a crucial role in immunity and development. They contain leucine-rich repeat domains, one transmembrane domain, and one Toll/IL-1 receptor domain. TLRs have been classified into V-type/scc and P-type/mcc TLRs, based on differences in the leucine-rich repea...

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Detalles Bibliográficos
Autores principales: Orús-Alcalde, Andrea, Lu, Tsai-Ming, Børve, Aina, Hejnol, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609888/
https://www.ncbi.nlm.nih.gov/pubmed/34809567
http://dx.doi.org/10.1186/s12862-021-01927-1

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