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Genome-Guided Discovery of Natural Products through Multiplexed Low-Coverage Whole-Genome Sequencing of Soil Actinomycetes on Oxford Nanopore Flongle

Genome mining is an important tool for discovery of new natural products; however, the number of publicly available genomes for natural product-rich microbes such as actinomycetes, relative to human pathogens with smaller genomes, is small. To obtain contiguous DNA assemblies and identify large (ca....

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Detalles Bibliográficos
Autores principales: Rajwani, Rahim, Ohlemacher, Shannon I., Zhao, Gengxiang, Liu, Hong-Bing, Bewley, Carole A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609971/
https://www.ncbi.nlm.nih.gov/pubmed/34812649
http://dx.doi.org/10.1128/mSystems.01020-21