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Genome-Guided Discovery of Natural Products through Multiplexed Low-Coverage Whole-Genome Sequencing of Soil Actinomycetes on Oxford Nanopore Flongle
Genome mining is an important tool for discovery of new natural products; however, the number of publicly available genomes for natural product-rich microbes such as actinomycetes, relative to human pathogens with smaller genomes, is small. To obtain contiguous DNA assemblies and identify large (ca....
Autores principales: | Rajwani, Rahim, Ohlemacher, Shannon I., Zhao, Gengxiang, Liu, Hong-Bing, Bewley, Carole A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609971/ https://www.ncbi.nlm.nih.gov/pubmed/34812649 http://dx.doi.org/10.1128/mSystems.01020-21 |
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