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Comparison of clinical, laboratory and radiological features in confirmed and unconfirmed COVID-19 patients
Background: We aimed to compare the clinical, laboratory and radiological findings of confirmed COVID-19 and unconfirmed patients. Methods: This was a single-center, retrospective study. Results: Overall, 620 patients (338 confirmed COVID-19 and 282 unconfirmed) were included. Confirmed COVID‐19 pat...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Future Medicine Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610070/ https://www.ncbi.nlm.nih.gov/pubmed/34812057 http://dx.doi.org/10.2217/fmb-2021-0162 |
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author | Surme, Serkan Tuncer, Gulsah Copur, Betul Zerdali, Esra Nakir, Inci Yilmaz Yazla, Meltem Bayramlar, Osman Faruk Buyukyazgan, Ahmet Kurt Cinar, Ayse Ruhkar Balli, Hatice Kurekci, Yesim Pehlivanoglu, Filiz Sengoz, Gonul |
author_facet | Surme, Serkan Tuncer, Gulsah Copur, Betul Zerdali, Esra Nakir, Inci Yilmaz Yazla, Meltem Bayramlar, Osman Faruk Buyukyazgan, Ahmet Kurt Cinar, Ayse Ruhkar Balli, Hatice Kurekci, Yesim Pehlivanoglu, Filiz Sengoz, Gonul |
author_sort | Surme, Serkan |
collection | PubMed |
description | Background: We aimed to compare the clinical, laboratory and radiological findings of confirmed COVID-19 and unconfirmed patients. Methods: This was a single-center, retrospective study. Results: Overall, 620 patients (338 confirmed COVID-19 and 282 unconfirmed) were included. Confirmed COVID‐19 patients had higher percentages of close contact with a confirmed or probable case. In univariate analysis, the presence of myalgia and dyspnea, decreased leukocyte, neutrophil and platelet counts were best predictors for SARS-CoV-2 RT-PCR positivity. Multivariate analyses revealed that only platelet count was an independent predictor for SARS-CoV-2 RT-PCR positivity. Conclusion: Routine complete blood count may be helpful for distinguishing COVID-19 from other respiratory illnesses at an early stage, while PCR testing is unique for the diagnosis of COVID-19. |
format | Online Article Text |
id | pubmed-8610070 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Future Medicine Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-86100702021-11-26 Comparison of clinical, laboratory and radiological features in confirmed and unconfirmed COVID-19 patients Surme, Serkan Tuncer, Gulsah Copur, Betul Zerdali, Esra Nakir, Inci Yilmaz Yazla, Meltem Bayramlar, Osman Faruk Buyukyazgan, Ahmet Kurt Cinar, Ayse Ruhkar Balli, Hatice Kurekci, Yesim Pehlivanoglu, Filiz Sengoz, Gonul Future Microbiol Research Article Background: We aimed to compare the clinical, laboratory and radiological findings of confirmed COVID-19 and unconfirmed patients. Methods: This was a single-center, retrospective study. Results: Overall, 620 patients (338 confirmed COVID-19 and 282 unconfirmed) were included. Confirmed COVID‐19 patients had higher percentages of close contact with a confirmed or probable case. In univariate analysis, the presence of myalgia and dyspnea, decreased leukocyte, neutrophil and platelet counts were best predictors for SARS-CoV-2 RT-PCR positivity. Multivariate analyses revealed that only platelet count was an independent predictor for SARS-CoV-2 RT-PCR positivity. Conclusion: Routine complete blood count may be helpful for distinguishing COVID-19 from other respiratory illnesses at an early stage, while PCR testing is unique for the diagnosis of COVID-19. Future Medicine Ltd 2021-11-23 2021-10 /pmc/articles/PMC8610070/ /pubmed/34812057 http://dx.doi.org/10.2217/fmb-2021-0162 Text en © 2021 Future Medicine Ltd https://creativecommons.org/licenses/by/4.0/This work is licensed under the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/) |
spellingShingle | Research Article Surme, Serkan Tuncer, Gulsah Copur, Betul Zerdali, Esra Nakir, Inci Yilmaz Yazla, Meltem Bayramlar, Osman Faruk Buyukyazgan, Ahmet Kurt Cinar, Ayse Ruhkar Balli, Hatice Kurekci, Yesim Pehlivanoglu, Filiz Sengoz, Gonul Comparison of clinical, laboratory and radiological features in confirmed and unconfirmed COVID-19 patients |
title | Comparison of clinical, laboratory and radiological features in confirmed and unconfirmed COVID-19 patients |
title_full | Comparison of clinical, laboratory and radiological features in confirmed and unconfirmed COVID-19 patients |
title_fullStr | Comparison of clinical, laboratory and radiological features in confirmed and unconfirmed COVID-19 patients |
title_full_unstemmed | Comparison of clinical, laboratory and radiological features in confirmed and unconfirmed COVID-19 patients |
title_short | Comparison of clinical, laboratory and radiological features in confirmed and unconfirmed COVID-19 patients |
title_sort | comparison of clinical, laboratory and radiological features in confirmed and unconfirmed covid-19 patients |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610070/ https://www.ncbi.nlm.nih.gov/pubmed/34812057 http://dx.doi.org/10.2217/fmb-2021-0162 |
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