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Comparison of clinical, laboratory and radiological features in confirmed and unconfirmed COVID-19 patients

Background: We aimed to compare the clinical, laboratory and radiological findings of confirmed COVID-19 and unconfirmed patients. Methods: This was a single-center, retrospective study. Results: Overall, 620 patients (338 confirmed COVID-19 and 282 unconfirmed) were included. Confirmed COVID‐19 pat...

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Autores principales: Surme, Serkan, Tuncer, Gulsah, Copur, Betul, Zerdali, Esra, Nakir, Inci Yilmaz, Yazla, Meltem, Bayramlar, Osman Faruk, Buyukyazgan, Ahmet, Kurt Cinar, Ayse Ruhkar, Balli, Hatice, Kurekci, Yesim, Pehlivanoglu, Filiz, Sengoz, Gonul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610070/
https://www.ncbi.nlm.nih.gov/pubmed/34812057
http://dx.doi.org/10.2217/fmb-2021-0162
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author Surme, Serkan
Tuncer, Gulsah
Copur, Betul
Zerdali, Esra
Nakir, Inci Yilmaz
Yazla, Meltem
Bayramlar, Osman Faruk
Buyukyazgan, Ahmet
Kurt Cinar, Ayse Ruhkar
Balli, Hatice
Kurekci, Yesim
Pehlivanoglu, Filiz
Sengoz, Gonul
author_facet Surme, Serkan
Tuncer, Gulsah
Copur, Betul
Zerdali, Esra
Nakir, Inci Yilmaz
Yazla, Meltem
Bayramlar, Osman Faruk
Buyukyazgan, Ahmet
Kurt Cinar, Ayse Ruhkar
Balli, Hatice
Kurekci, Yesim
Pehlivanoglu, Filiz
Sengoz, Gonul
author_sort Surme, Serkan
collection PubMed
description Background: We aimed to compare the clinical, laboratory and radiological findings of confirmed COVID-19 and unconfirmed patients. Methods: This was a single-center, retrospective study. Results: Overall, 620 patients (338 confirmed COVID-19 and 282 unconfirmed) were included. Confirmed COVID‐19 patients had higher percentages of close contact with a confirmed or probable case. In univariate analysis, the presence of myalgia and dyspnea, decreased leukocyte, neutrophil and platelet counts were best predictors for SARS-CoV-2 RT-PCR positivity. Multivariate analyses revealed that only platelet count was an independent predictor for SARS-CoV-2 RT-PCR positivity. Conclusion: Routine complete blood count may be helpful for distinguishing COVID-19 from other respiratory illnesses at an early stage, while PCR testing is unique for the diagnosis of COVID-19.
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spelling pubmed-86100702021-11-26 Comparison of clinical, laboratory and radiological features in confirmed and unconfirmed COVID-19 patients Surme, Serkan Tuncer, Gulsah Copur, Betul Zerdali, Esra Nakir, Inci Yilmaz Yazla, Meltem Bayramlar, Osman Faruk Buyukyazgan, Ahmet Kurt Cinar, Ayse Ruhkar Balli, Hatice Kurekci, Yesim Pehlivanoglu, Filiz Sengoz, Gonul Future Microbiol Research Article Background: We aimed to compare the clinical, laboratory and radiological findings of confirmed COVID-19 and unconfirmed patients. Methods: This was a single-center, retrospective study. Results: Overall, 620 patients (338 confirmed COVID-19 and 282 unconfirmed) were included. Confirmed COVID‐19 patients had higher percentages of close contact with a confirmed or probable case. In univariate analysis, the presence of myalgia and dyspnea, decreased leukocyte, neutrophil and platelet counts were best predictors for SARS-CoV-2 RT-PCR positivity. Multivariate analyses revealed that only platelet count was an independent predictor for SARS-CoV-2 RT-PCR positivity. Conclusion: Routine complete blood count may be helpful for distinguishing COVID-19 from other respiratory illnesses at an early stage, while PCR testing is unique for the diagnosis of COVID-19. Future Medicine Ltd 2021-11-23 2021-10 /pmc/articles/PMC8610070/ /pubmed/34812057 http://dx.doi.org/10.2217/fmb-2021-0162 Text en © 2021 Future Medicine Ltd https://creativecommons.org/licenses/by/4.0/This work is licensed under the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/)
spellingShingle Research Article
Surme, Serkan
Tuncer, Gulsah
Copur, Betul
Zerdali, Esra
Nakir, Inci Yilmaz
Yazla, Meltem
Bayramlar, Osman Faruk
Buyukyazgan, Ahmet
Kurt Cinar, Ayse Ruhkar
Balli, Hatice
Kurekci, Yesim
Pehlivanoglu, Filiz
Sengoz, Gonul
Comparison of clinical, laboratory and radiological features in confirmed and unconfirmed COVID-19 patients
title Comparison of clinical, laboratory and radiological features in confirmed and unconfirmed COVID-19 patients
title_full Comparison of clinical, laboratory and radiological features in confirmed and unconfirmed COVID-19 patients
title_fullStr Comparison of clinical, laboratory and radiological features in confirmed and unconfirmed COVID-19 patients
title_full_unstemmed Comparison of clinical, laboratory and radiological features in confirmed and unconfirmed COVID-19 patients
title_short Comparison of clinical, laboratory and radiological features in confirmed and unconfirmed COVID-19 patients
title_sort comparison of clinical, laboratory and radiological features in confirmed and unconfirmed covid-19 patients
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610070/
https://www.ncbi.nlm.nih.gov/pubmed/34812057
http://dx.doi.org/10.2217/fmb-2021-0162
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