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Restoration of aged hematopoietic cells by their young counterparts through instructive microvesicles release
This study addresses the potential to reverse age-associated morbidity by establishing methods to restore the aged hematopoietic system. Parabiotic animal models indicated that young secretome could restore aged tissues, leading us to establish a heterochronic transwell system with aged mobilized pe...
Autores principales: | Greco, Steven J., Ayer, Seda, Guiro, Khadidiatou, Sinha, Garima, Donnelly, Robert J., El-Far, Markos H., Sherman, Lauren S., Kenfack, Yannick, Pamarthi, Sri Harika, Gergues, Marina, Sandiford, Oleta A., Schonning, Michael J., Etchegaray, Jean-Pierre, Rameshwar, Pranela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610119/ https://www.ncbi.nlm.nih.gov/pubmed/34762598 http://dx.doi.org/10.18632/aging.203689 |
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