Mutations in DNA damage response pathways as a potential biomarker for immune checkpoint blockade efficacy: evidence from a seven-cancer immunotherapy cohort

Recently several studies have demonstrated the implications of mutations in DNA damage response (DDR) pathways for immune checkpoint blockade (ICB) treatment. However, smaller sample sizes, lesser cancer types, and the lack of multivariate-adjusted analyses may produce unreliable results. From the M...

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Detalles Bibliográficos
Autores principales: Zhang, Wenjing, Zhang, Liwen, Jiang, Hao, Li, Yuting, Wang, Suzhen, Wang, Qinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610133/
https://www.ncbi.nlm.nih.gov/pubmed/34747718
http://dx.doi.org/10.18632/aging.203670

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