Cargando…

Curcumol inhibits malignant biological behaviors and TMZ-resistance in glioma cells by inhibiting long noncoding RNA FOXD2-As1-promoted EZH2 activation

Currently, conventional treatment is not sufficient to improve the survival of glioma patients. Hence, adopting novel personalized treatment programs is imperative. Curcumol, a Chinese herbal medicine extract from the roots of Rhizoma Curcumae, has attracted significant interest due to its beneficia...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lv, Xuyang, Sun, Jiangchuan, Hu, Linfeng, Qian, Ying, Fan, Chunlei, Tian, Nan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610140/ https://www.ncbi.nlm.nih.gov/pubmed/34739394 http://dx.doi.org/10.18632/aging.203662

Ejemplares similares

ATRX/EZH2 complex epigenetically regulates FADD/PARP1 axis, contributing to TMZ resistance in glioma
por: Han, Bo, et al.
Publicado: (2020)

Hispidulin Enhances Temozolomide (TMZ)-Induced Cytotoxicity against Malignant Glioma Cells In Vitro by Inhibiting Autophagy
por: Chen, Zhihua, et al.
Publicado: (2022)

TOPK inhibits autophagy by phosphorylating ULK1 and promotes glioma resistance to TMZ
por: Lu, Hui, et al.
Publicado: (2019)

FoxD2-AS1 is a prognostic factor in glioma and promotes temozolomide resistance in a O(6)-methylguanine-DNA methyltransferase-dependent manner
por: Shangguan, Wenbing, et al.
Publicado: (2019)

Curcumol Attenuates Endometriosis by Inhibiting the JAK2/STAT3 Signaling Pathway
por: Wang, Yan, et al.
Publicado: (2022)

Antitumor effects of ribavirin in combination with TMZ and IFN-β in malignant glioma cells
por: Ochiai, Yushi, et al.
Publicado: (2020)

Curcumol inhibits encephalomyocarditis virus by promoting IFN-β secretion
por: Zheng, Jiangang, et al.
Publicado: (2021)

Bortezomib inhibits growth and sensitizes glioma to temozolomide (TMZ) via down-regulating the FOXM1–Survivin axis
por: Tang, Jun-Hai, et al.
Publicado: (2019)

Curcumol inhibits EMCV replication by activating CH25H and inhibiting the formation of ROs
por: Zheng, Jiangang, et al.
Publicado: (2022)

Self-assembled angiopep-2 modified lipid-poly (hypoxic radiosensitized polyprodrug) nanoparticles delivery TMZ for glioma synergistic TMZ and RT therapy
por: Zong, Zhenkun, et al.
Publicado: (2019)

Curcumol Synergizes with Cisplatin in Osteosarcoma by Inhibiting M2-like Polarization of Tumor-Associated Macrophages
por: Wang, Jincheng, et al.
Publicado: (2022)

Benefits and Challenges of Inhibiting EZH2 in Malignant Pleural Mesothelioma
por: Al Khatib, MHD Ouis, et al.
Publicado: (2023)

Human Glioma Cells Therapy Using ATRA-Induced Differentiation Method to Promote the Inhibitive Effect of TMZ and CCDP
por: Li, Xinning, et al.
Publicado: (2021)

Pro-inflammatory activity of long noncoding RNA FOXD2-AS1 in Achilles tendinopathy
por: Ke, Xiaoting, et al.
Publicado: (2023)

MiR-32 Inhibits Proliferation and Metastasis by Targeting EZH2 in Glioma
por: Zhang, Yuan, et al.
Publicado: (2019)

miR-4306 inhibits the malignant behaviors of colorectal cancer by regulating lncRNA FoxD2-AS1
por: Ye, Jinjun, et al.
Publicado: (2021)

Retracted: Human Glioma Cells Therapy Using ATRA-Induced Differentiation Method to Promote the Inhibitive Effect of TMZ and CCDP
por: Healthcare Engineering, Journal of
Publicado: (2023)

Knockdown of BCL6 Inhibited Malignant Phenotype and Enhanced Sensitivity of Glioblastoma Cells to TMZ through AKT Pathway
por: Song, Wen, et al.
Publicado: (2018)

Targeting Glioma Stem Cells through Combined BMI1 and EZH2 Inhibition
por: Jin, Xun, et al.
Publicado: (2017)

Radiosensitization of Glioma Cells by Temozolomide (TMZ): A Colony Formation Assay
por: Babaloui, Somayyeh, et al.
Publicado: (2022)

LOXL2 Upregulation in Gliomas Drives Tumorigenicity by Activating Autophagy to Promote TMZ Resistance and Trigger EMT
por: Zhang, Qing, et al.
Publicado: (2020)

Inhibition of microglial EZH2 leads to anti-tumoral effects in pediatric diffuse midline gliomas
por: Keane, Lily, et al.
Publicado: (2021)

Curcumol inhibits the malignant progression of prostate cancer and regulates the PDK1/AKT/mTOR pathway by targeting miR-9
por: Sheng, Wen, et al.
Publicado: (2021)

EZH2 is a potential prognostic predictor of glioma
por: Chen, Yi‐nan, et al.
Publicado: (2020)

Targeted Disruption of the EZH2/EED Complex Inhibits EZH2-dependent Cancer
por: Kim, Woojin, et al.
Publicado: (2013)

Curcumol Inhibits the Development of Prostate Cancer by miR-125a/STAT3 Axis
por: Sheng, Wen, et al.
Publicado: (2022)

Phase 1 study of temozolamide (TMZ) combined with procarbazine (PCB) in patients with gliomas
por: Newlands, E S, et al.
Publicado: (2003)

Effects of valproic acid on the susceptibility of human glioma stem cells for TMZ and ACNU
por: Li, Zhiying, et al.
Publicado: (2018)

Experimental study of selective MGMT peptides mimicking TMZ drug resistance in glioma
por: Wu, Yue, et al.
Publicado: (2022)

Long Noncoding RNA FOXD2-AS1 Promotes the Malignancy of Cervical Cancer by Sponging MicroRNA-760 and Upregulating Hepatoma-Derived Growth Factor
por: Dou, Xiaoqing, et al.
Publicado: (2020)

A novel series of phenolic temozolomide (TMZ) esters with 4 to 5-fold increased potency, compared to TMZ, against glioma cells irrespective of MGMT expression
por: Shervington, Leroy, et al.
Publicado: (2020)

EZH2 in Myeloid Malignancies
por: Rinke, Jenny, et al.
Publicado: (2020)

EZH2-Inhibited MicroRNA-454-3p Promotes M2 Macrophage Polarization in Glioma
por: Qi, Bin, et al.
Publicado: (2020)

Long noncoding RNA Neat1 modulates myogenesis by recruiting Ezh2
por: Wang, Shanshan, et al.
Publicado: (2019)

TRPC5 mediates TMZ resistance in TMZ-resistant glioblastoma cells via NFATc3-P-gp pathway
por: Zou, Yan, et al.
Publicado: (2021)

Conventionally fractionated stereotactic radiotherapy (CFRT) in combination with dose-dense temozolomide (TMZ) in relapsed malignant glioma: A case report
por: Qie, Shuai, et al.
Publicado: (2019)

The Sequence of Delta24-RGD and TMZ Administration in Malignant Glioma Affects the Role of CD8(+)T Cell Anti-tumor Activity
por: Kleijn, Anne, et al.
Publicado: (2017)

Long noncoding RNA GAS5 promotes bladder cancer cells apoptosis through inhibiting EZH2 transcription
por: Wang, Miao, et al.
Publicado: (2018)

Plasma long noncoding RNAs PANDAR, FOXD2-AS1, and SMARCC2 as potential novel diagnostic biomarkers for gastric cancer
por: Yang, Ziwei, et al.
Publicado: (2019)

Curcumol potentiates celecoxib-induced growth inhibition and apoptosis in human non-small cell lung cancer
por: Cai, Fangfang, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_a4m92h6rrch23ie5518re4j2qv