LncRNA MIR31HG is induced by tocilizumab and ameliorates rheumatoid arthritis fibroblast-like synoviocyte-mediated inflammation via miR-214-PTEN-AKT signaling pathway

Fibroblast-like synoviocytes (FLS) obtained from the joint synovium of rheumatoid arthritis (RA) patients exhibit hyperplasia and aggressive inflammatory phenotypes. This study was designed to explore the anti-inflammatory mechanism of IL-6R inhibitor, tocilizumab, in FLS-mediated inflammation in RA...

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Detalles Bibliográficos
Autores principales: Cao, Liang, Jiang, Haifeng, Yang, Jing, Mao, Jun, Wei, Guofeng, Meng, Xiangyun, Zang, Hongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610144/
https://www.ncbi.nlm.nih.gov/pubmed/34753831
http://dx.doi.org/10.18632/aging.203644

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