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Evaluation of 30 DNA damage response and 6 mismatch repair gene mutations as biomarkers for immunotherapy outcomes across multiple solid tumor types

OBJECTIVE: DNA damage response (DDR) genes have low mutation rates, which may restrict their clinical applications in predicting the outcomes of immune checkpoint inhibitor (ICI) treatment. Thus, a systemic analysis of multiple DDR genes is needed to identify potential biomarkers of ICI efficacy. ME...

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Detalles Bibliográficos
Autores principales:	Gong, Zhe, Yang, Yue, Zhang, Jieyun, Guo, Weijian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Compuscript 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610155/ https://www.ncbi.nlm.nih.gov/pubmed/33960179 http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0351

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