Single-cell transcriptome profiling and the use of AID deficient mice reveal that B cell activation combined with antibody class switch recombination and somatic hypermutation do not benefit the control of experimental trypanosomosis

Salivarian trypanosomes are extracellular protozoan parasites causing infections in a wide range of mammalian hosts, with Trypanosoma evansi having the widest geographic distribution, reaching territories far outside Africa and occasionally even Europe. Besides causing the animal diseases, T. evansi...

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Detalles Bibliográficos
Autores principales: Nguyen, Hang Thi Thu, Guevarra, Robin B., Magez, Stefan, Radwanska, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610246/
https://www.ncbi.nlm.nih.gov/pubmed/34762705
http://dx.doi.org/10.1371/journal.ppat.1010026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610246/
https://www.ncbi.nlm.nih.gov/pubmed/34762705
http://dx.doi.org/10.1371/journal.ppat.1010026

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