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Network-based protein-protein interaction prediction method maps perturbations of cancer interactome

The perturbations of protein-protein interactions (PPIs) were found to be the main cause of cancer. Previous PPI prediction methods which were trained with non-disease general PPI data were not compatible to map the PPI network in cancer. Therefore, we established a novel cancer specific PPI predict...

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Detalles Bibliográficos
Autores principales: Qiu, Jiajun, Chen, Kui, Zhong, Chunlong, Zhu, Sihao, Ma, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610286/
https://www.ncbi.nlm.nih.gov/pubmed/34727106
http://dx.doi.org/10.1371/journal.pgen.1009869