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Network-based protein-protein interaction prediction method maps perturbations of cancer interactome
The perturbations of protein-protein interactions (PPIs) were found to be the main cause of cancer. Previous PPI prediction methods which were trained with non-disease general PPI data were not compatible to map the PPI network in cancer. Therefore, we established a novel cancer specific PPI predict...
Autores principales: | Qiu, Jiajun, Chen, Kui, Zhong, Chunlong, Zhu, Sihao, Ma, Xiao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610286/ https://www.ncbi.nlm.nih.gov/pubmed/34727106 http://dx.doi.org/10.1371/journal.pgen.1009869 |
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