The gene expression and bioinformatic analysis of choline trimethylamine-lyase (CutC) and its activating enzyme (CutD) for gut microbes and comparison with their TMA production levels

Recent studies revealed that some intestinal microorganisms anaerobically convert choline to trimethylamine (TMA) by choline TMA-lyase (cutC). TMA is further oxidized to trimethylamine-N-oxide (TMAO), by the liver enzyme flavin-dependent monooxygenase 3 (FMO3). TMA in the serum is correlated with th...

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Detalles Bibliográficos
Autores principales: Ramireddy, Latha, Tsen, Hau-Yang, Chiang, Yu-Chen, Hung, Chen Ying, Chen, Fu-Chih, Yen, Hsien- Tung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610359/
https://www.ncbi.nlm.nih.gov/pubmed/34841334
http://dx.doi.org/10.1016/j.crmicr.2021.100043

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